Sherlock Holmes: The Case of the Silver Earring (known in North America as Secret of the Silver Earring and as Sherlock Holmes: The Silver Earring) is a computer game developed by Frogwares and published in 2004 on two CD-ROMs for Microsoft Windows by Digital Jesters in Europe and Ubisoft in North America. While the game is "inspired by The Adventures of Sherlock Holmes," it uses an original plotline — set in London in 1897 — and allows the player to investigate a murder as Sherlock Holmes and Dr. John H. Watson. A version for Wii was also released in Europe in 2011.

The second in the Adventures of Sherlock Holmes series of adventure games developed by Frogwares, it was preceded by the 2002 game Sherlock Holmes: The Mystery of the Mummy, and was followed by Sherlock Holmes: The Awakened in 2006. The game acts as a prequel to Mystery of the Mummy - despite being released two years after the earlier game, it is actually set two years earlier (in 1897 as opposed to 1899). However, it is revealed in Sherlock Holmes: Nemesis (set in July 1895) that the events of this game are set before Holmes' encounter with Arsene Lupin, therefore creating a continuity error in the series.