Onimusha 2: Samurai's Destiny, released in Japan as Onimusha 2 (鬼武者2 Onimusha Tsū?), is an action-adventure game developed and released by Capcom for the PlayStation 2. It is the second installment in the Onimusha series of video games released in May 2002. Set in medieval Japan, the plot revolves around a new protagonist, Jubei Yagyu, who is on a quest of revenge as he battles a demon army led by Nobunaga Oda, a sinister warlord who eliminated the Yagyu clan. Across his quest, Jubei learns of his oni heritage which grants him powers to slay the demons and meets new allies who also wish to defeat Nobunaga.

The game retains the action elements from its predecessor such as the use of multiple special weapons that can be upgraded by defeating enemies. Apart from the main character, the game features four playable sub-characters, each of whom shares a part in the story. The player's actions determine which characters will decide to help Jubei in his quest. These characters were added by the Capcom staff to give a bigger depth to the game and expand the game's feeling of adventure.

Publications for video games generally praised Onimusha 2 for keeping the action elements from its prequel and adding new gameplay elements. The game also sold a total of 1.9 million units as of 2008.